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Global variations in omega-3 fatty acid status and omega-6:omega-3 ratios: insights from > 500,000 whole-blood dried blood spot samples
https://lipidworld.biomedcentral.com/articles/10.1186/s12944-025-02676-6
Publication Date: August 9, 2025
Journal: Lipids in Health and Disease.
Analysis: The study analyzed data from more than 590,000 dried blood spot (DBS) samples from Zinzino's proprietary BalanceTest database, the world's largest of its kind.
Key Findings: The study revealed widespread omega-3 deficiency and imbalanced omega-6:omega-3 ratios across diverse global populations, even among individuals already taking various omega-3 supplements.
Study Product Note: Zinzino's specific omega-3 supplement, BalanceOil+, was not part of the evaluation in this particular study, as the analysis focused on the global population's baseline fatty acid status. The study primarily validates the necessity of objective testing to measure nutritional status.
Other Relevant Information
Zinzino states that the published data provides hard evidence that their "test-based nutrition" approach is valid and helps shape global nutrition science.
The company emphasizes that its BalanceTest is a scientifically validated, standardized method for assessing omega-3 status.
Zinzino has indicated that the next frontier lies in demonstrating how their specific formulation (BalanceOil+ with polyphenols) helps close the nutritional gap, building on the baseline data from the published study
Importance of maintaining a low omega–6/omega–3 ratio for reducing inflammation
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